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Molecular Systems Biology_Drug-microenvironment interactions in chronic lymphocytic leukaemia
EMBO Reports _ ARHGAP11B expands basal progenitors in ape cerebral organoids to human levels
Robert Signer Lab — Hsf1 promotes hematopoietic stem cell fitness and proteostasis in response to ex vivo culture stress and aging
Aadel Chaudhuri Lab — Washington University St. Louis. Circulating tumor DNA shed by tumors into the bloodstream has been shown to be a potent liquid biomarker of cancer.
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Josh Andersen Lab — BioID reveals an ATG9A interaction with ATG13-ATG101 in the degradation of p62/SQSTM1-ubiquitin clusters
Issam Ben Sahra Lab — Northwestern University. Control of SAM abundance and RNA methylation by mTORC1 signaling.
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Robert Signer Lab — Hsf1 promotes hematopoietic stem cell fitness and proteostasis in response to ex vivo culture stress and aging
Jennifer Trowbridge Lab — The Jackson Laboratory.
Nathan Singh Lab — Washington University in St. Louis. Antigen-independent activation enhances the efficacy of 41BB co-stimulated CD22 CAR T cells.
Margaret Goodell Lab — Baylor College of Medicine. Tissue-Biased Expansion of DNMT3A-Mutant Clones in a Mosaic Individual Is Associated with Conserved Epigenetic Erosion.
Omar Abdel-Wahab Lab — Memorial Sloan Kettering Cancer Center. Mutant SF3B1 promotes AKT and NF-kB driven mammary tumorigenesis.
Katherine King Lab — Baylor College of Medicine. Interferon gamma mediates hematopoietic stem cell activation and niche relocalization through BST2.
Benjamin Deneen Lab — Baylor College of Medicine. Region-Specific Transcriptional Control of Astrocyte Function Oversees Local Circuit Activities.
Katherine King Lab — Baylor College of Medicine. Interferon gamma mediates hematopoietic stem cell activation and niche relocalization through BST2.
Nathan Singh Lab — Washington University in St. Louis. Antigen-independent activation enhances the efficacy of 41BB co-stimulated CD22 CAR T cells.
Alessandro Vindigni Lab — Washington University in STL. PRIMPOL-Mediated Adaptive Response Suppresses Replication Fork Reversal in BRCA-Deficient Cells.
Margaret Goodell Lab — Baylor College of Medicine. Tissue-Biased Expansion of DNMT3A-Mutant Clones in a Mosaic Individual Is Associated with Conserved Epigenetic Erosion.
Omar Abdel-Wahab Lab — Memorial Sloan Kettering Cancer Center. Mutant SF3B1 promotes AKT and NF-kB driven mammary tumorigenesis.
Omar Abdel-Wahab Lab — Memorial Sloan Kettering Cancer Center, and Justin Taylor — Sylvester Comprehensive Cancer Center. Germ cell tumors and associated hematologic malignancies evolve from a common shared precursor.
Yonathan Arfi — University of Bordeaux
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Jennifer Trowbridge Lab — The Jackson Laboratory.
Yonathan Arfi — University of Bordeaux
Margaret Goodell Lab — Baylor College of Medicine. Tissue-Biased Expansion of DNMT3A-Mutant Clones in a Mosaic Individual Is Associated with Conserved Epigenetic Erosion.
Benjamin Deneen Lab — Baylor College of Medicine. Region-Specific Transcriptional Control of Astrocyte Function Oversees Local Circuit Activities.
Grant Challen — Washington University in STL. Dnmt3a and Dnmt3b Have Overlapping and Distinct Functions in Hematopoietic Stem Cells.
Margaret Goodell Lab — Baylor College of Medicine. Mutant NPM1 Maintains the Leukemic State through HOX Expression.
Jeffrey Magee Lab — Washington University in STL. Single-Cell Analysis of Neonatal HSC Ontogeny Reveals Gradual and Uncoordinated Transcriptional Reprogramming that Begins before Birth.
Margaret Goodell Lab — Baylor College of Medicine. PPM1D Mutations Drive Clonal Hematopoiesis in Response to Cytotoxic Chemotherapy.
Omar Abdel-Wahab Lab — Memorial Sloan Kettering Cancer Center, and Justin Taylor — Sylvester Comprehensive Cancer Center. Germ cell tumors and associated hematologic malignancies evolve from a common shared precursor.
Margaret Goodell Lab, Erez Lieberman Aiden Lab — Baylor College of Medicine, and Xiaotian Zhang Lab — VAI Van Andel Institute. Large DNA Methylation Nadirs Anchor Chromatin Loops Maintaining Hematopoietic Stem Cell Identity.
Jeffrey Magee Lab — Washington University in STL. Single-Cell Analysis of Neonatal HSC Ontogeny Reveals Gradual and Uncoordinated Transcriptional Reprogramming that Begins before Birth.